To succeed in the pharmaceutical market, companies must – among other factors – join the big pharma Club – represented by top 15 pharmaceutical companies. The 15 largest pharmaceutical companies in the U.S. account for ~90% of the industry’s total market share, and ~100% of the industry’s profit.
Pharma companies rely on various strategies to remain competitive. They invest in internal capability development and explore promising candidates (in the pipeline or commercialized) through product/company acquisitions and alliances to increase market share. While an in-depth business fundamental benchmarking is an invaluable exercise to understand the long-term strategic intent, annual revenue ranking of the pharmaceutical companies is perhaps the quick and the best gauge of their execution abilities.
On the basis of revenue, below are the top 15 U.S. pharmaceutical companies in 2016. The rankings of the top 15 pharmaceutical companies in the US have been compiled from R&P US Top 3000 database – R&P Screener.
Companies in this list include both pharmaceutical and biotechnology companies.
Top 15 US Pharmaceutical Companies By 2016 Revenues
| 2016 Rank | Company | 2015 Revenues | 2016 Revenues | YoY Revenue Growth | 2016 Net Income | 2016 Net Margin |
|---|---|---|---|---|---|---|
| 1 | J&J | 70,074 | 71,890 | 2.6% | 16,540 | 23.0% |
| 2 | PFIZER | 48,851 | 52,824 | 8.1% | 7,215 | 13.7% |
| 3 | MERCK & CO. | 39,498 | 39,807 | 0.8% | 3,920 | 9.8% |
| 4 | GILEAD | 32,639 | 30,390 | -6.9% | 13,501 | 44.4% |
| 5 | ABBVIE | 22,859 | 25,638 | 12.2% | 5,953 | 23.2% |
| 6 | AMGEN | 21,662 | 22,991 | 6.1% | 7,722 | 33.6% |
| 7 | ELI LILLY | 19,959 | 21,222 | 6.3% | 2,738 | 12.9% |
| 8 | ABBOTT | 20,405 | 20,853 | 2.2% | 1,400 | 6.7% |
| 9 | BMS | 16,560 | 19,427 | 17.3% | 4,457 | 22.9% |
| 10 | ALLERGAN | 12,688 | 14,571 | 14.8% | 14,973 | 102.8% |
| 11 | BIOGEN | 10,764 | 11,449 | 6.4% | 3,703 | 32.3% |
| 12 | SHIRE | 6,417 | 11,397 | 77.6% | 327 | 2.9% |
| 13 | CELGENE | 9,256 | 11,229 | 21.3% | 1,999 | 17.8% |
| 14 | MYLAN | 9,429 | 11,077 | 17.5% | 480 | 4.3% |
| 15 | VALEANT | 10,447 | 9,674 | -7.4% | -2,409 | -24.9% |
Top 15 US Pharmaceutical Companies By 2016 Revenues
1. Johnson & Johnson
Johnson & Johnson ranked No. 1 in R&P Top 15 US Pharmaceutical Companies list, is a holding company. The Company and its subsidiaries are engaged in the research and development, manufacture and sale of a range of products in the healthcare field. The Company operates through three segments: Consumer, Pharmaceutical and Medical Devices. You can learn about legal action against the drug maker in this article on USALegal.com.
2. Pfizer
Pfizer Inc., ranked No. 2 in R&P Top 15 US Pharmaceutical Companies list, is a research-based global biopharmaceutical company. The Company is engaged in the discovery, development, and manufacture of healthcare products. Its global portfolio includes medicines and vaccines, as well as consumer healthcare products. The Company manages its commercial operations through two business segments: Pfizer Innovative Health (IH) and Pfizer Essential Health (EH).
3. Merck & Co
Merck & Co., ranked No. 3 in R&P Top 15 US Pharmaceutical Companies list, is a global healthcare company. The Company offers health solutions through its prescription medicines, vaccines, biologic therapies and animal health products. It operates through four segments: Pharmaceutical, Animal Health, Healthcare Services, and Alliances.
4. Gilead Sciences
Gilead Sciences ranked No. 4 in R&P Top 15 US Pharmaceutical Companies list, is a research-based biopharmaceutical company that discovers, develops and commercializes medicines in areas of unmet medical need. Its products include AmBisome, Atripla, Cayston, Complera/Eviplera, Descovy, Emtriva, Epclusa, Genvoya, Harvoni, Hepsera, Letairis, Odefsey, Ranexa, Sovaldi, Stribild, Truvada, Tybost, Vemlidy, Viread, Vitekta and Zydelig. The Company’s areas of focus include HIV; liver diseases, such as chronic hepatitis C virus (HCV) infection and chronic hepatitis B virus (HBV) infection; hematology/oncology; cardiovascular, and inflammation/respiratory diseases.
5. Abbvie
AbbVie Inc. ranked No. 5 in R&P Top 15 US Pharmaceutical Companies list is a research-based biopharmaceutical company. It offers products in various categories, including HUMIRA (adalimumab), Oncology products, Virology Products, Additional Virology products, Metabolics/Hormones products, Endocrinology products and other products.
6. Amgen
Amgen Inc. ranked No. 6 in R&P Top 15 US Pharmaceutical Companies list, is a biotechnology company. The Company discovers, develops, manufactures and delivers various human therapeutics. The Company operates in the human therapeutics segment. The Company’s marketed products portfolio includes Neulasta (pegfilgrastim); erythropoiesis-stimulating agents (ESAs), such as Aranesp (darbepoetin alfa) and EPOGEN (epoetin alfa); Sensipar/Mimpara (cinacalcet); XGEVA (denosumab); Prolia (denosumab); NEUPOGEN (filgrastim), and other marketed products, such as KYPROLIS (carfilzomib), Vectibix (panitumumab), Nplate (romiplostim), Repatha (evolocumab), BLINCYTO (blinatumomab), IMLYGIC (talimogene laherparepvec) and Corlanor (ivabradine).
7. Eli Lilly & Co.
Eli Lilly and Company ranked No. 7 in R&P Top 15 US Pharmaceutical Companies list, is engaged in medication manufacturing business. The Company discovers, develops, manufactures and markets products in two segments: human pharmaceutical products and animal health products. The Company’s human pharmaceutical business segment sells medicines, which are discovered or developed by its scientists. Its animal health business segment operates through the Company’s Elanco division, which develops, manufactures and markets products for both food animals and companion animals.
8. Abbott
Abbott Laboratories ranked No. 8 in R&P Top 15 US Pharmaceutical Companies list, is engaged in the discovery, development, manufacture and sale of a range of healthcare products. The Company operates through four segments: Established Pharmaceutical Products, Diagnostic Products, Nutritional Products and Vascular Products. The Company, through St. Jude Medical, Inc., also offers a range of products, such as rhythm management products, electrophysiology products, heart failure related products, vascular products, structural heart products and neuromodulation products.
9. Bristol Myers Squibb
Bristol-Myers Squibb Company ranked No. 9 in R&P Top 15 US Pharmaceutical Companies list, is engaged in the discovery, development, licensing, manufacturing, marketing, distribution and sale of biopharmaceutical products. The Company’s pharmaceutical products include chemically-synthesized medications, or small molecules, and products produced from biological processes called biologics. The Company’s products include Empliciti, Opdivo, Sprycel, Yervoy, Eliquis, Orencia, Baraclude, Hepatitis C Franchise, Reyataz Franchise and Sustiva Franchise.
10. Allergan
Allergan plc ranked No. 10 in R&P Top 15 US Pharmaceutical Companies list, is a specialty pharmaceutical company. The Company is engaged in the development, manufacturing, marketing and distribution of brand-name pharmaceutical products, medical aesthetics, biosimilar and over-the-counter (OTC) pharmaceutical products. The Company operates through three segments: US Specialized Therapeutics, US General Medicine, and International.
11. Biogen
Biogen Inc. ranked No. 11 in R&P Top 15 US Pharmaceutical Companies list, is a biopharmaceutical company. The Company focuses on discovering, developing, manufacturing and delivering therapies to people living with serious neurological, rare and autoimmune diseases. The Company markets products, including TECFIDERA, AVONEX, PLEGRIDY, TYSABRI, ZINBRYTA and FAMPYRA for multiple sclerosis (MS), FUMADERM for the treatment of severe plaque psoriasis and SPINRAZA for the treatment of spinal muscular atrophy (SMA).
12. Shire
Shire plc ranked No. 12 in R&P Top 15 US Pharmaceutical Companies list, is a biotech company focused on serving people with rare diseases and other specialized conditions. The Company’s segment is engaged in research, development, licensing, manufacturing, marketing, distribution and sale of specialist medicines. The Company focuses its development resources on projects in various therapeutic areas (TAs), including Neuroscience, Ophthalmology, Hematology, Oncology, Immunology, Gastrointestinal (GI)/Metabolic/Endocrinology Diseases.
13. Celgene
Celgene Corporation ranked No. 13 in R&P Top 15 US Pharmaceutical Companies list, is an integrated global biopharmaceutical company. The Company, together with its subsidiaries, is engaged in the discovery, development, and commercialization of therapies for the treatment of cancer and inflammatory diseases through solutions in protein homeostasis, immuno-oncology, epigenetics, immunology and neuroinflammation.
14. Mylan
Mylan N.V. ranked No. 14 in R&P Top 15 US Pharmaceutical Companies list, is a global pharmaceutical company. The Company develops, licenses, manufactures, markets and distributes generic, brand-name and over-the-counter (OTC) products in a range of dosage forms and therapeutic categories. It operates through three segments on a geographic basis, North America, Europe and Rest of World.
15. Valeant
Valeant Pharmaceuticals International, Inc., ranked No. 15 in R&P Top 15 US Pharmaceutical Companies list, is a specialty pharmaceutical and medical device company. The Company is engaged in developing, manufacturing, and marketing a range of branded, generic and branded generic pharmaceuticals, over-the-counter (OTC) products, and medical devices (contact lenses, intraocular lenses, ophthalmic surgical equipment and aesthetics devices). The Company operates through two segments: Developed Markets and Emerging Markets. In the Developed Markets segment, it focuses on the areas of dermatology, neurology, gastrointestinal (GI) disorders, and eye health therapeutic classes. In the Emerging Markets segment, it focuses primarily on branded generics, OTC products, and medical devices.
The rankings of the top 15 pharmaceutical companies in the US have been compiled from R&P US Top 3000 database – R&P Screener.
